发明名称 NEW OXAZOLIDIN AND INDOLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
摘要 PURPOSE: A novel oxazolidin and indole compounds are provided to suppress IL-6 or IL-11 signal system and use as an agent for anti-cancer and anti-inflammation. CONSTITUTION: A novel oxazolidin and indole compound is denoted by chemical formula 1. In chemical formula 1, R1 is hydrogen, straight, side, or cyclo alkyl of C1-C10, or substituted or non-substituted benzyl; and R2 is hydrogen or straight, side, or cyclo alkyl of C1-C10. A pharmaceutical composition for preventing and treating cancer or inflammatory diseases contains the compound of chemical formula 1 or pharmaceutically acceptable salt. The inflammatory disease is caused by IL-6 or IL-11.
申请公布号 KR20100086745(A) 申请公布日期 2010.08.02
申请号 KR20090006136 申请日期 2009.01.23
申请人 KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY 发明人 RHO, MUN CHUAL;KIM, YOUNG KOOK;CHOI, YONG SEOK;LEE, KYEONG;CHOI, JUNG HO;LEE, WOO SONG;LEE, SEUNG WOONG;PARK, SU JIN;CHANG, JONG SUN;JUNG, HWA YOUNG
分类号 C07D263/18;C07D263/08;C07D263/10 主分类号 C07D263/18
代理机构 代理人
主权项
地址