发明名称 |
NEW OXAZOLIDIN AND INDOLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME |
摘要 |
PURPOSE: A novel oxazolidin and indole compounds are provided to suppress IL-6 or IL-11 signal system and use as an agent for anti-cancer and anti-inflammation. CONSTITUTION: A novel oxazolidin and indole compound is denoted by chemical formula 1. In chemical formula 1, R1 is hydrogen, straight, side, or cyclo alkyl of C1-C10, or substituted or non-substituted benzyl; and R2 is hydrogen or straight, side, or cyclo alkyl of C1-C10. A pharmaceutical composition for preventing and treating cancer or inflammatory diseases contains the compound of chemical formula 1 or pharmaceutically acceptable salt. The inflammatory disease is caused by IL-6 or IL-11.
|
申请公布号 |
KR20100086745(A) |
申请公布日期 |
2010.08.02 |
申请号 |
KR20090006136 |
申请日期 |
2009.01.23 |
申请人 |
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY |
发明人 |
RHO, MUN CHUAL;KIM, YOUNG KOOK;CHOI, YONG SEOK;LEE, KYEONG;CHOI, JUNG HO;LEE, WOO SONG;LEE, SEUNG WOONG;PARK, SU JIN;CHANG, JONG SUN;JUNG, HWA YOUNG |
分类号 |
C07D263/18;C07D263/08;C07D263/10 |
主分类号 |
C07D263/18 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|