发明名称 N-CARBAMOYLMETHYL-4(R)-PHENYL-2-PYRROLIDINONE, METHOD OF ITS PREPARATION AND PHARMACEUTICAL USE
摘要 <p>The invention relates to the R-enantiomer of N-carbamoylmethyl-4-phenyl-2-pyrrolidinone (R-Carphedon) of pharmacological value. The method of its preparation includes the N-alkylation of 4(R)-phenyl-2-pyrrolidinone with ethyl bromoacetate in the presence of a strong base and the treatment of intermediate N-ethoxycarbonylmethyl-4(R)-phenyl-2-pyrrolidinone with ammonia.</p>
申请公布号 SI2013166(T1) 申请公布日期 2010.07.30
申请号 SI20070030253T 申请日期 2007.03.15
申请人 AKCIJU SABIEDRIBA "OLAINFARM" 发明人 VEINBERG GRIGORY;VORONA MAKSIM;ZVEJNIECE LIGA;CHERNOBROVIJS ALEKSANDRS;KALVINSH IVARS;KARINA LIGITA;DAMBROVA MAIJA
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