Aryl and heteroaryl-piperidinecarboxylate derivatives, the preparation and the use thereof in the form of FAAH enzyme inhibitors

摘要

The disclosure relates to enzyme inhibitors and their use in the treatment and therapy of a wide variety of diseases and degenerative conditions. More particularly, it is directed towards the use of aryl and heteroaryl-piperidinecarboxylate derivatives of formula (I), processes for their preparation and methods of use thereof as fatty acid amido hydrolase (FAAH) enzyme inhibitors in the treatment of arthritis, heart disease, cancer and the like and to their application in a wide variety of therapeutic regimens such as for the treatment of pain, inflammation, neurodegenerative diseases, etc.