6-(Pyridinyl)-4-pyrimidone derivates as tau protein kinase 1 inhibitors

摘要

Disclosed is a compound represented by the formula (I), an optically active isomer thereof or a pharmaceutically acceptable salt thereof, wherein R5 is represented by formula (II) and A represents a C6-C10 aryl or heterocycle and the remaining substituents are as defined in the specification, and its use in the treatment of neurodegenerative disease.