发明名称 METHODS FOR THE DETECTION OF FATTY-ACYLATED PROTEIN
摘要 Sensitive, non-radioactive fatty-acyls of Formula I are useful in in vivo methods for detection and cellular imaging of a fatty-acylated substrate (e.g., protein or polypeptide). In Formula I the symbols X and A, and the subscript n are as described herein. These fatty-acyl compounds are can be used, inter alia, for analyzing the lipid composition of proteins in different biological states under various cellular conditions, and serve as a gateway into global lipidomic analysis of cellular proteins.
申请公布号 US2010189660(A1) 申请公布日期 2010.07.29
申请号 US20100704796 申请日期 2010.02.12
申请人 GENENTECH, INC. 发明人 HANNOUSH RAMI N.
分类号 A61K49/00;C07C57/18 主分类号 A61K49/00
代理机构 代理人
主权项
地址