Pulmonary surfactant formulations and methods for promoting mucus clearance
摘要
Methods and compositions to enhance mucus clearance and to treat pulmonary lung disorders such as cystic fibrosis are disclosed. The methods utilize compositions including synthetic pulmonary surfactants having one or more phospholipids and a synthetic polypeptide, administered alone or combined with hyperosmotic agents, to patients in an amount effective to enhance mucus clearance.
申请公布号
ZA200902487(B)
申请公布日期
2010.07.28
申请号
ZA20090002487
申请日期
2007.09.19
申请人
DISCOVERY LABORATORIES, INC.
发明人
JOHNSON, MARK E.;SEGAL, ROBERT;HOFMANN, THOMAS;CAPETOLA, ROBERT J.