| 发明名称 |
Polynucleotides encoding chimeric GFP-aequorin as bioluminescent Ca++ reporters |
| 摘要 |
A modified bioluminescent system comprising a fluorescent molecule covalently linked with a photoprotein, wherein said link between the two proteins has the function to stabilize the modified bioluminescent system and allowing the transfer of the energy by Chemiluminescence Resonance Energy Transfer (CRET).
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| 申请公布号 |
US7763443(B2) |
申请公布日期 |
2010.07.27 |
| 申请号 |
US20050149177 |
申请日期 |
2005.06.10 |
| 申请人 |
INSTITUT PASTEUR;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
BAUBET VALERIE;LE MOUELLIC HERVE;BRULET PHILIPPE |
| 分类号 |
C12P21/06;G01N33/483;A61K49/00;C07K7/06;C07K7/08;C07K14/00;C07K14/435;C07K19/00;C12N1/21;C12N15/09;C12Q1/02;G01N21/76 |
主分类号 |
C12P21/06 |
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