发明名称 METHOD OF OBTAINING MEDICAL COMPOSITION, BASED ON INCREASE OF CRYSTAL MICRO PARTICLES SURFACE AFFINITY TO ACTIVE AGENTS
摘要 FIELD: medicine. ^ SUBSTANCE: invention relates to method of adsorbing active agents, in particular proteins or peptides, on the surface of crystal diketopiperazine microparticles, which includes stages of obtaining water suspension of diketopiperazine microparticles and active agent, change of superficial properties of microparticle by changing conditions of suspending, for instance changing solution pH or polarity. ^ EFFECT: adsorbing of active agent on microparticle takes place independently on stage of solvent removal. ^ 26 cl, 17 dwg, 4 tbl, 7 ex
申请公布号 RU2394550(C2) 申请公布日期 2010.07.20
申请号 RU20080114306 申请日期 2006.09.14
申请人 MANNKAJND KORPOREJSHN 发明人 OBERG KIT A.
分类号 A61J3/00;A61K9/16;A61K38/22;A61K47/22 主分类号 A61J3/00
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