发明名称 NOVEL THIAZOLES DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS
摘要 <p>The present invention relates to novel compounds of Formula (I), wherein M, P, A and (B)n are defined as in Formula (I); invention compounds are modulators of metabotropic glutamate receptors - subtype 4 ("mGluR4") which are useful for the treatment or prevention of central nervous system disorders as well as other disorders modulated by mGluR4 receptors. The invention is also directed to pharmaceutical compositions and the use of such compounds in the manufacture of medicaments, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGluR4 is involved.</p>
申请公布号 WO2010079239(A1) 申请公布日期 2010.07.15
申请号 WO2010EP50305 申请日期 2010.01.12
申请人 ADDEX PHARMA S.A.;BOLEA, CHRISTELLE 发明人 BOLEA, CHRISTELLE
分类号 C07D417/12;A61K31/427;A61P25/16;C07D417/14 主分类号 C07D417/12
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