| 发明名称 |
NEW 5-ETHYNYLPYRAZOLE-3-CARBOXAMIDE DERIVATIVE EXHIBITING 5-HT2B RECEPTOR ANTAGONISM |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a medicine or a medicinal composition comprising as an effective ingredient a compound exhibiting 5-HT<SB>2B</SB>receptor antagonism, and to provide a medicine or a medicinal composition that exhibits highly selective affinity for the receptor and moderates various unfavorable actions or toxicity such as QT elongation in which the receptor is involved by reducing, as an antagonistic compound, involvement of the receptor in other receptors. Ž<P>SOLUTION: The compound represented by general formula (I) or a pharmacologically acceptable salt thereof is provided. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
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| 申请公布号 |
JP2010155802(A) |
申请公布日期 |
2010.07.15 |
| 申请号 |
JP20080334756 |
申请日期 |
2008.12.26 |
| 申请人 |
RAQUALIA PHARMA INC |
发明人 |
YAMAGISHI TATSUYA;KAWAMURA KIYOSHI |
| 分类号 |
C07D231/14;A61K31/415;A61K31/4155;A61K31/427;A61K31/454;A61K31/5377;A61P1/00;A61P1/04;A61P1/10;A61P1/12;A61P1/16;A61P3/04;A61P9/10;A61P9/12;A61P9/14;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P19/02;A61P25/00;A61P25/04;A61P25/06;A61P25/22;A61P25/24;A61P25/28;A61P29/00;A61P35/00;A61P43/00;C07D401/06;C07D409/06;C07D417/06 |
主分类号 |
C07D231/14 |
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