The subject of the invention is a vaginal suppository with improved efficacy containing an antifungal active ingredient, wherein the said active ingredient is present simultaneously in dissolved and suspended form in the suppository base containing polyethylene-glycol and polysorbate. The ratio of the suspended and dissolved active ingredient in the suppository is reproducible and said ratio does not change during the storage. A further subject of the present invention is a process for manufacturing said pharmaceutical formulations.
申请公布号
WO2010079373(A1)
申请公布日期
2010.07.15
申请号
WO2010HU00003
申请日期
2010.01.08
申请人
EGIS GYOGYSZERGYAR, NYILVANOSAN, MUEKOEDOE;MIKULASIK, ENDRE;SZAKALY, PETER