| 摘要 |
PURPOSE: A producing method of a crotonic acid derivative is provided to reduce the content of an impurity, and to mass produce the crotonic acid derivative. CONSTITUTION: A producing method of a crotonic acid derivative comprises the following: forming a compound marked with chemical formula 7 by reacting a compound marked with chemical formula 6 under the presences of a base; and forming the crotonic acid derivative marked with chemical formula 1 by performing a hydrolysis with the compound marked with the chemical formula 7. In the chemical formulas, R2 is an alkyl group with the carbon number of 1~8. R is either an alkyl group with the carbon number of 1~5, or a phenyl group.
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