发明名称 SPIRO-CONDENSED 1, 3, 4-THIADIAZOLE DERIVATIVES FOR INHIBITING KSP KINESIN ACTIVITY.
摘要 <p>The present invention relates to compounds of Formula (I), below, (wherein X, R1, R2, R3, p, E, ring A, and ring B are as defined herein). The present invention also relates to compositions (including pharmaceutically acceptable compositions) comprising these compounds, alone and in combination with one or more additional therapeutic agents, and to methods for their use in inhibiting KSP kinesin activity, and for treating cellular proliferative diseases or disorders associated with KSP kinesin activity. Formula I [Chemical formula should be inserted here as it appears on abstract in paper form.].</p>
申请公布号 MX2010004312(A) 申请公布日期 2010.07.05
申请号 MX20100004312 申请日期 2008.10.16
申请人 SCHERING CORPORATION. 发明人 SIDDIQUI, M. ARSHAD;DAI, CHAOYANG;MANSOOR, UMAR FARUK;YANG, LIPING;VITHARANA, LALALNTHI DILRUKSHI;ANGELES, ANGIE R.
分类号 C07D285/14;A61K31/433;A61P35/00;C07D515/10;C07D515/20 主分类号 C07D285/14
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