| 摘要 |
The present invention relates to analogs of cortistatin A, J, K, and L, having the general formula: I and salts thereof, wherein R1, R2, R3, R4, n, and m are as defined herein; processes for preparing such compounds and intermediates thereto; pharmaceutical compositions comprising such compounds; methods for treating a proliferative disease; methods for treating a disease associated with aberrant angiogenesis; methods for inhibiting angiogenesis; and processes for preparing cortistatin A, J, K, and L, and analogs thereof. |
| 申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;FLYER, ALEC, NATHANSON;LEE, HONG, MYUNG;MYERS, ANDREW, G.;NIETO-OBERHUBER, CRISTINA, MONTSERRAT;SHAIR, MATTHEW, D.;SI, CHONG |
发明人 |
FLYER, ALEC, NATHANSON;LEE, HONG, MYUNG;MYERS, ANDREW, G.;NIETO-OBERHUBER, CRISTINA, MONTSERRAT;SHAIR, MATTHEW, D.;SI, CHONG |
