发明名称 |
MENINGOCOCCAL VACCINE FORMULATIONS |
摘要 |
A lyophilised formulation for vaccines against Neisseria meningitidis comprises (i) an immunogen for raising an immune response against N.meningitidis serogroup B, and (ii) a conjugated capsular saccharide from one or more of N.meningitidis serogroups A, C, W135 and/or Y. The lyophilised antigens can be reconstituted into liquid form at the time of use ready for administration to a patient, and reconstitution can use an adjuvant comprising an oil-in-water emulsion. The formulation gives excellent result in terms of both stability and immunogenicity. |
申请公布号 |
EP2200642(A1) |
申请公布日期 |
2010.06.30 |
申请号 |
EP20080838605 |
申请日期 |
2008.10.17 |
申请人 |
NOVARTIS AG |
发明人 |
CONTORNI, MARIO;KAZZAZ, JINA;O'HAGAN, DEREK;SINGH, MANMOHAN;UGOZZOLI, MILDRED |
分类号 |
A61K39/095 |
主分类号 |
A61K39/095 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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