发明名称 NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID
摘要 [PROBLEMS] To provide: a compound effective as an amyloid-targeting diagnostic imaging probe; and a reagent for detecting amyloid deposited on a biological tissue, which comprises the compound. [MEANS FOR SOLVING PROBLEMS] Disclosed are: a compound represented by the formula shown below; and a reagent for detecting amyloid deposited on a biological tissue, which comprises the compound. Wherein R, Rand Rindependently represent a group selected from the group consisting of a hydrogen, a hydroxyl group, an alkyl substituent having 1 to 4 carbon atoms, an alkoxy substituent having 1 to 4 carbon atoms in its alkyl chain, and a halogen substituent (provided that all of at least two substituents selected from R, Rand Rcannot represent a hydrogen); Rrepresents a group selected from the group consisting of a hydrogen, a hydroxyl group, an alkoxy substituent having 1 to 4 carbon atoms in its alkyl chain, a halogen substituent; and m represents an integer of 1 to 4, provided that at least one of R, R, Rand Rrepresents a radioactive halogen substituent.
申请公布号 KR20100072344(A) 申请公布日期 2010.06.30
申请号 KR20107010119 申请日期 2008.10.24
申请人 NIHON MEDI-PHYSICS CO., LTD. 发明人 TANIFUJI SHIGEYUKI;NAKAMURA DAISAKU;TAKASAKI SHINYA;OKUMURA YUKI
分类号 C07D471/04;A61K49/00;A61K49/04;A61P25/28 主分类号 C07D471/04
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