Recombinant adeno-associated virus vector for expressing beta-amyloid peptide in intestinal cells to treat Alzheimer's disease

摘要

Disclosed is the use of an adeno-associated virus vector in the manufacture of a therapeutic agent to express the beta-amyloid peptide in intestinal cells for the treatment of Alzheimer's disease, wherein the adeno-associated virus vector comprises DNA encoding said beta-amyloid peptide and DNA encoding a signal peptide capable of extracellularly secreting said beta-amyloid peptide, in an operative form.