METHODS FOR CONTROLLED SEEDING OF ADHERENT CELL TYPES ON HIGH DENSITY PATTERNED CELL CULTURES

摘要

The present invention relates to the fields of life sciences and biological processes. Specifically, the invention relates to microarrays and live cell based screening and molecular analysis. More specifically, the present invention relates to novel methods for the screening of the effects of a test compound on adherent cells, for molecular analysis of adherent cells and for producing a microarray. The present invention also relates to cell arrays and the use of said arrays for molecular analysis of adherent cells or for screening agents. Furthermore, the present invention also relates to the use of said arrays to explore effects from one type of adherent cells to the other, to screen for drug targets essential for cancer, to screen for synthetic lethal effects of test compounds and/or to compare functional response from one type of adherent cells to another.