| 发明名称 |
RAPID DETECTION OF ANTIBIOTIC RESISTANCE IN MYCOBACTERIUM TUBERCULOSIS |
| 摘要 |
2134103 9322454 PCTABS00027 Multidrug resistant strains of Mycobacterium tuberculosis represent a considerable threat to public health worldwide. Resistance to isoniazid (INH), rifampicin or analogues thereof, or streptomycin, i.e. key components of anti-tuberculosis regimens, need frequently to be detected. The invention involves the detection of a mutation in either the katG gene (isoniazid resistance), the rpoB gene (rifampicin resistance) or rpsL gene (streptomycin resistance). |
| 申请公布号 |
CA2134103(C) |
申请公布日期 |
2010.06.22 |
| 申请号 |
CA19932134103 |
申请日期 |
1993.04.30 |
| 申请人 |
INSTITUT PASTEUR;MEDICAL RESEARCH COUNCIL;UNIVERSITE PIERRE ET MARIE CURIE;UNIVERSITE DE BERNE;ASSISTANCE PUBLIQUE HOPITAUX DE PARIS |
发明人 |
HEYM, BEATE;COLE, STEWART;YOUNG, DOUGLAS;ZHANG, YING;HONORE, NADINE;TELENTI, AMALIO;BODMER, THOMAS |
| 分类号 |
C12N15/09;C12Q1/68;C07H21/00;C12N9/08;C12Q1/18;C12R1/32;G01N33/15;G01N33/50 |
主分类号 |
C12N15/09 |
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