| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention refers to novel aminoalkyl-and amodialkylbenzopyran derivatives of the general formula (I): (a), where (a) group is a substitute in 6 or 7 position, where R is mono- or bicyclic (C6-C10)-aryl radical optionally substituted with one or two substitutes selected out of linear or ramified (C1-C5)-alkyls, linear or ramified (C1-C5)-alkoxy, hydroxy, halogen and trifluoromethyl; m is zero or integer 1-3; n, p, R1 and R2 are as indicated in the description, and both R3 and R4 are hydrogen or both are oxygen: and to pharmaceutically acceptable salts thereof. ^ EFFECT: selective reversible MAO-B inhibitors in vitro and in vivo, applicable as medicines for prevention and treatment of degenerative central nervous system disorders. ^ 13 cl, 24 ex |
