| 发明名称 |
POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF |
| 摘要 |
Disclosed are compounds having polybasic functionalities. The compounds inhibit bacterial efflux pump inhibitors and are used in combination with an anti-bacterial agent to treat or prevent bacterial infections. These combinations can be effective against bacterial infections that have developed resistance to anti-bacterial agents through an efflux pump mechanism.
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| 申请公布号 |
US2010152098(A1) |
申请公布日期 |
2010.06.17 |
| 申请号 |
US20090613329 |
申请日期 |
2009.11.05 |
| 申请人 |
MPEX PHARMACEUTICALS, INC. |
发明人 |
GLINKA TOMASZ;RODNY OLGA;BOSTIAN KEITH A.;WALLACE DAVID M.;HIGUCHI ROBERT I.;CHOW CHUN;MAK CHI CHING;HIRST GAVIN;EASTMAN BRIAN |
| 分类号 |
A61K38/05;A61K31/472;A61K38/02;A61P31/04;A61P31/06;A61P31/08;C07C237/20;C07C311/46;C07D207/14;C07D209/20;C07D211/06;C07D211/58;C07D213/643;C07D213/74;C07D215/38;C07D217/22;C07D231/12;C07D241/42;C07D265/30;C07D307/79;C07D309/10;C07D319/18;C07D321/10;C07D333/24 |
主分类号 |
A61K38/05 |
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