1, 3, 5 -TRIAZ INE DERIVATIVES USEFUL IN THE TREATMENT OF CHRONIC PAIN DISORDERS
摘要
The present invention provides compounds that are inhibitors of voltage-gated sodium channel (Nav), in particular Nav 1.7 and are therefore useful for the treatment of diseases 5 treatable by inhibition of these channels, in particular, chronic pain disorders. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
申请公布号
WO2010022055(A3)
申请公布日期
2010.06.17
申请号
WO2009US54169
申请日期
2009.08.18
申请人
AMGEN INC.;BUCHANAN, JOHN L.;BREGMAN, HOWARD;CHAKKA, NAGASREE;DIMAURO, ERIN F.;DU, BINGFAN;NGUYEN, HANH NHO;ZHENG, XIAO MEI
发明人
BUCHANAN, JOHN L.;BREGMAN, HOWARD;CHAKKA, NAGASREE;DIMAURO, ERIN F.;DU, BINGFAN;NGUYEN, HANH NHO;ZHENG, XIAO MEI