发明名称 SUBSTITUTED IMIDAZOHETEROCYCLE DERIVATIVES
摘要 The present invention provides substituted imidazoheterocycles having the general structure of formula (I), wherein Y is chosen from -O-, -OCRgRh-, -CRgRhO-, -CRgRh-, -(CRgRh)2-, -NRi-, -CRgRhNRi- and -NRiCRgRh-. Also provided are pharmaceutically acceptable salts, acid salts, hydrates, solvates and stereoisomers of the compounds of formula I. The compounds are useful as modulators of cannabinoid receptors and for the prophylaxis and treatment of cannabinoid receptor-associated diseases and conditions, such as pain, inflammation and pruritis.
申请公布号 WO2010068520(A2) 申请公布日期 2010.06.17
申请号 WO2009US66172 申请日期 2009.12.01
申请人 CARA THERAPEUTICS, INC.;O'CONNOR, STEPHEN, J.;NEWCOM, JASON, S.;RALBOVSKY, JANET, L.;GUSTAFSON, GARY, R.;BECKETT, R., PAUL;LUO, ROBERT, XHIYONG 发明人 O'CONNOR, STEPHEN, J.;NEWCOM, JASON, S.;RALBOVSKY, JANET, L.;GUSTAFSON, GARY, R.;BECKETT, R., PAUL;LUO, ROBERT, XHIYONG
分类号 C07D487/04;A61K31/4162;A61P17/04;A61P29/00 主分类号 C07D487/04
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