| 摘要 |
The present invention is directed to compounds, compositions and methods for treating or preventing viral infections, in particular, HIV, and HBV, in human patients or other animal hosts. The compounds are 3'-azido-2',3'-dideoxy purine monophosphates, and pharmaceutically acceptable, salts, prodrugs, and other derivatives thereof. In particular, the compounds show potent antiviral activity against HIV-1 and HBV. |
| 申请人 |
RFS PHARMA, LLC;SCHINAZI, RAYMOND, F.;MELLORS, JOHN, W.;SLUIS-CREMER, NICOLAS, PAUL;AMBLARD, FRANK;COATS, STEVEN, J.;SHI, JUNXING;WHITAKER, RICHARD, ANTHONY;EMORY UNIVERSITY;UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |
发明人 |
SCHINAZI, RAYMOND, F.;MELLORS, JOHN, W.;SLUIS-CREMER, NICOLAS, PAUL;AMBLARD, FRANK;COATS, STEVEN, J.;SHI, JUNXING;WHITAKER, RICHARD, ANTHONY |
