| 发明名称 |
RNA INTERFERENCE MEDIATING SMALL RNA MOLECULE |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a new material mediating other target specific nucleic acid modification such as a target specific RNA interference or DNA methylation, etc. <P>SOLUTION: The synthesized and isolated double-stranded RNA molecules, wherein the RNA molecules can be subjected to a target specific modification, and the double-stranded RNA molecules have a first and a second RNA strands, and either of the first or the second RNA strand is modified or blocked by 3' ends, and this allows the initiation of a dsRNA processing at the 3' end of the facing RNA strand molecules are provided. <P>COPYRIGHT: (C)2010,JPO&INPIT |
| 申请公布号 |
JP2010131031(A) |
申请公布日期 |
2010.06.17 |
| 申请号 |
JP20100046471 |
申请日期 |
2010.03.03 |
| 申请人 |
MAX-PLANCK-GES ZUR FOERDERUNG DER WISSENSCHAFTEN EV;EUROPEAN MOLECULAR BIOLOGY LAB |
发明人 |
TUSCHL THOMAS;ELBASHIR SAYDA;LENDECKEL WINFRIED;WILM MATTHIAS;LUEHRMANN REINHARD |
| 分类号 |
A01H5/00;C12N15/09;A01K67/027;A61K9/00;A61K31/7105;A61K38/00;A61K45/00;A61K48/00;A61P31/12;A61P35/00;A61P37/02;A61P43/00;C07H;C07H21/00;C12N;C12N1/00;C12N5/10;C12N15/10;C12N15/113;C12P21/02;C12Q1/02;C12Q1/68;G01N33/15;G01N33/50;G01N33/68 |
主分类号 |
A01H5/00 |
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