发明名称 ESTROGENIC EXTRACTS OF RHEUM PALMATUM L OF THE POLYGONACEAE FAMILY AND USES THEREOF
摘要 <p>Extracts of various species of the Polygonaceae family have estrogenic properties. For example, aqueous and ethanolic extracts of Rheum palmatum L of the Polygonaceae family species possess estrogenic properties in both ERalpha+ and ERbeta+ cells. These estrogenic effects include estrogen response element (ERE) stimulation as well as tumor necrosis factor (TNF) repression. Methods are provided for treating climacteric symptoms, breast and/or uterine cancer, and osteoporosis.</p>
申请公布号 EP2194997(A1) 申请公布日期 2010.06.16
申请号 EP20080829078 申请日期 2008.09.05
申请人 BIONOVO INC. 发明人 COHEN, ISAAC
分类号 A61K36/70 主分类号 A61K36/70
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