FRAGMENTS OF DOUBLE-CHAIN RNA HAVING ANTIPROLIFERATIVE AND INTERFERON-INDUCING ACTIVITY

摘要

FIELD: chemistry; biochemistry. ^ SUBSTANCE: invention relates to molecular biology and biotechnology. Proposed are fragments of double-chain RNA with length of 22 nucleotides which contain trinucleotide projecting 3'-ends consisting of nucleotide chains of the following sequence: 5'-AAAN1N2N3N4N5N6N7GCCUGACACUUU/A-3' 5'-GUGUCAGGCN14N13N12N11N10N9N8UUUUUU/A-3', where N1-N7 are complementary to N8-N14, respectively, having antiproliferative and interferon-inducing activity. ^ EFFECT: obtaining compounds which can be used for making dosage forms of preparations used for treating viral diseases. ^ 5 dwg 2 tbl, 6 ex