A compound having Formula I or II (Formula I) or (Formula II), or a pharmaceutically acceptable salt thereof, wherein X, Z, R1, R2, R11 and R12 are as defined in the specification; pharmaceutical compositions thereof; and methods of use thereof.
申请公布号
US2010135954(A1)
申请公布日期
2010.06.03
申请号
US20080597275
申请日期
2008.04.25
申请人
EXELIXIS, INC.
发明人
TSUHAKO AMY L.;AAY NAING;BROWN S. DAVID;CHAN WAI KI VICKY;DU HONGWANG;HUANG PING;KANE BRIAN;KEARNEY PATRICK;KIM MOON HWAN;KOLTUN ELENA S.;PACK MICHAEL;XU WEI;ZHOU PEIWEN