SINGLE DOMAIN ANTIBODY - TARGETED NANOPARTICLE ARCHITECTURES FOR INCREASED PATHOGEN DETECTION SPECIFICITY AND SENSITIVITY
摘要
<p>A conjugate comprising a superparamagnetic nanoparticle (SPN) coupled to at least one single-domain antibody (sd Ab) specific to a pathogen or cell of interest. The SPN may comprise an iron oxide core and a silica shell and may be labelled with SERS-active Raman reporter molecule, or a detectable label.</p>
申请公布号
WO2010060209(A1)
申请公布日期
2010.06.03
申请号
WO2009CA01712
申请日期
2009.11.24
申请人
NATIONAL RESEARCH COUNCIL OF CANADA;TANHA, JAMSHID;KELL, ARNOLD, J.;SIMARD, BENOIT
