发明名称 |
ANTIBODY-TARGETED CARRIER FOR CONTRAST AGENTS |
摘要 |
<p>A nanoconjugate is formed from a self-assembled unilamellar vesicle (ULV), at least one contrast agent which may be a MRI contrast agent, a radioisotope or a fluorophore, and at least one antibody, which may be an IgG or an antibody fragment such as a single-domain antibody. The nanoconjugate be targetted with the antibody to receptors specific to certain disease states, and thus be used in diagnostic and imaging methods using the properties o contrast agent.</p> |
申请公布号 |
WO2010060217(A1) |
申请公布日期 |
2010.06.03 |
申请号 |
WO2009CA01729 |
申请日期 |
2009.11.26 |
申请人 |
NATIONAL RESEARCH COUNCIL OF CANADA;ABULROB, ABEDNELNASSER;STANIMIROVIC, DANICA;IQBAL, UMAR;NIEH, MU-PING;KATSARAS, JOHN |
发明人 |
STANIMIROVIC, DANICA;IQBAL, UMAR;NIEH, MU-PING;KATSARAS, JOHN |
分类号 |
C07K17/02;A61K49/00;A61K49/16;A61K51/10;C07K16/00;C07K16/26;C07K16/28;G01N33/544 |
主分类号 |
C07K17/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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