摘要 |
<p>A compound having the structure I useful for treatment or prevention of cardiovascular diseases, endothelial dysfunction, diastolic dysfunction, atherosclerosis, hypertension, angina pectoris, thromboses, restenoses, myocardial infarction, strokes, cardiac insufficiency, pulmonary hypertonia, erectile dysfunction, asthma bronchiale, chronic kidney insufficiency, diabetes, or cirrhosis of the liver in a human or animal patient.</p> |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
KIM, RONALD M.;BITTNER, AMY R.;CHANG, JIANG;SINZ, CHRISTOPHER JOSEPH;TAN, QIANG;PARMEE, EMMA R.;MIRC, J. W. |