THE PREPARATION METHOD OF SUMATRIPTAN

摘要

PURPOSE: A method for manufacturing sumatriptan is provided to simplify process by reducing the amount of reagent and to massively produce sumatriptan at high purity and yield. CONSTITUTION: A sumatriptan compound of chemical formula 1 is prepared by reacting dimethyl amine of chemical formula 2((CH3_)_2NH) with hydroxyl indole compound of chemical formula 3. The preparation is performed under the presence of hydrogen at 1-5 pressure using a catalyst. The catalyst is copper oxide, chromium oxide, or silica.