发明名称 |
KIDNEY-SPECIFIC TUMOR VACCINE DIRECTED AGAINST KIDNEY TUMOR ANTIGEN G-250 |
摘要 |
This invention provides an anti-cancer immunogenic agent(s) (e.g. vaccines) that elicit an immune response specifically directed against renal cell cancers expressing a G250 antigenic marker. Preferred immunogenic agents comprise a chimeric molecule comprising a kidney cancer specific antigen (G250) attached to a granulocyte-macrophage colony stimulating factor (GM-CSF). The agents are useful in a wide variety of treatment modalities including, but not limited to protein vaccination, DNA vaccination, and adoptive immunotherapy.
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申请公布号 |
US2010129313(A1) |
申请公布日期 |
2010.05.27 |
申请号 |
US20090479415 |
申请日期 |
2009.06.05 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
BELLDEGRUN ARIE;TSO CHO-LEA |
分类号 |
C07K14/53;A61K38/00;A61K38/19;A61K39/00;A61P35/00;A61P35/04;C07K14/47;C12N5/02;C12N15/85;C12N15/86 |
主分类号 |
C07K14/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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