| 发明名称 |
Substituted isoquinolines and their use as rho-kinase inhibitors |
| 摘要 |
The invention relates to 6-substituted isoquinoline and isoquinoline derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds. |
| 申请公布号 |
ZA200903554(B) |
申请公布日期 |
2010.05.26 |
| 申请号 |
ZA20090003554 |
申请日期 |
2009.05.22 |
| 申请人 |
SANOFI-AVENTIS |
发明人 |
PLETTENBURG, OLIVER;LORENZ, KATRIN;GOERLITZER, JOCHEN;LOEHN, MATTHIAS |
| 分类号 |
A61K;A61P;C07D |
主分类号 |
A61K |
| 代理机构 |
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代理人 |
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| 主权项 |
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