Histone deacetylase inhibitors with combined activity on class-I and class-IIB histone deacetylases in combination with proteasome inhibitors

摘要

The present invention is concerned with combinations of a proteasome inhibitor and a histone deacetylase inhibitor with combined activity on class-I and class-IIB histone deacetylases, for inhibiting the growth of tumor cells, useful in the treatment of cancer.