发明名称 |
ORAL PHARMACEUTICAL COMPOSITION FOR SOFT CAPSULES CONTAINING VINORELBINE AND METHOD OF TREATMENT |
摘要 |
The invention described herein relates to a pharmaceutical composition containing vinorelbine as an active ingredient which is suitable for encapsulation in soft capsules. The liquid oral pharmaceutical composition suitable for a liquid fill composition for a soft capsule dosage form comprises: vinorelbine or a pharmaceutically acceptable salt thereof; ethanol; water; glycerol; and polyethylene glycol. In preferred embodiment, the tartrate salt form of vinorelbine is used in the composition. The invention also provides for a method of treating cancer comprising orally administering, to a patient in need of treatment thereof, a soft capsule comprising the pharmaceutical composition of the invention. |
申请公布号 |
PT1530459(E) |
申请公布日期 |
2010.05.20 |
申请号 |
PT20030731404T |
申请日期 |
2003.05.28 |
申请人 |
R.P. SCHERER TECHNOLOGIES, LLC |
发明人 |
ELIE LEVERD;JOEL BOUGARET;MARIE-MADELEINE BOHN;NORBERT HEINTZ |
分类号 |
A61K9/48;A61K9/64;A61K31/4745;A61K31/475;A61P35/00 |
主分类号 |
A61K9/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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