发明名称 |
ANTI-CD20 MONOCLONAL ANTIBODIES |
摘要 |
<p>It is intended to provide a monoclonal antibody having a growth inhibitory activity against a cell having a human CD20 antigen which is produced by using, as immunogens, a human B cell line expressing the human CD20 antigen and a cell line originating in a non-human animal, which is different from an animal to be immunized and has been transformed with human CD20 DNA, and a monoclonal antibody obtained by chimerization or humanization of the above-described monoclonal antibody. These monoclonal antibodies show biological activities suitable for using as drugs.</p> |
申请公布号 |
EP2186892(A1) |
申请公布日期 |
2010.05.19 |
申请号 |
EP20070806885 |
申请日期 |
2007.09.06 |
申请人 |
OSAKA UNIVERSITY |
发明人 |
UCHIYAMA, SUSUMU;FUKUI, KIICHI |
分类号 |
C12N15/09;A61K39/395;A61P35/00;A61P37/02;C07K16/28;C12N5/10;C12P21/08 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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