发明名称 |
METHOD OF PROVIDING PATIENT SPECIFIC IMMUNE RESPONSE IN AMYLOIDOSES AND PROTEIN AGGREGATION DISORDERS |
摘要 |
A treatment of Alzheimer's disease and other disorders involving protein misfolding or aggregation is provided by enhancing or sustaining an antibody response against predominantly directed against pathological protein aggregates or neo-epitopes present on pathogenic forms of said protein or protein complex. Furthermore, therapeutic methods are also described, wherein ex vivo stimulated antigen-selected peripheral blood lymphocytes are regrafted into the cognate donor. |
申请公布号 |
EP2185160(A2) |
申请公布日期 |
2010.05.19 |
申请号 |
EP20080785778 |
申请日期 |
2008.09.01 |
申请人 |
NEURIMMUNE THERAPEUTICS AG |
发明人 |
HENCO, KARSTEN;NITSCH, ROGER;GRIMM, JAN;ZELLER, ANJA;MAIER, MARCEL |
分类号 |
A61K31/7088;A61K39/39;A61P25/28 |
主分类号 |
A61K31/7088 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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