Methods and compositions for diagnosis and prognosis of renal injury and renal failure

摘要

The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect Hepatocyte growth factor and optionally one or more markers selected from the group consisting of Clusterin, Heart- type fatty acid binding protein, Interferon gamma, Interleukin- 12 subunit beta, Interleukin-16, Interleukin-2, 72 kDa type IV collagenase, Matrix metalloproteinase-9, Midkine, and Serum amyloid P-component as diagnostic and prognostic biomarkers in renal injuries.