发明名称 |
Methods for detecting therapeutic effects of anti-cancer drugs |
摘要 |
precancerous lesions, and subject having precancerous lesions and being treated with an anti-cancer agent; (2) isolating total microbial genomic DNA from the fecal samples to provide total microbial genomic DNA; (3) comparing the total microbial genomic DNA using fingerprint spectrum analysis; (4) identifying key fingerprint bands correlated with the effect of the anti-cancer agent; (5) identifying key microorganisms associated with the key fingerprint bands; (6) designing microbial sequence-specific primers and probes; and (7) determining the quantitative differences of the key microorganisms in fecal samples to identify an indicator microorganism for monitoring the effect of the anti-cancer agent.
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申请公布号 |
US2010112564(A1) |
申请公布日期 |
2010.05.06 |
申请号 |
US20090380103 |
申请日期 |
2009.02.23 |
申请人 |
SHANGHAI JIAO TONG UNIVERSITY |
发明人 |
ZHAO LIPING;HUA WEI;PANG XIAOYAN;WEI JIA;WU DAZHENG |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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