摘要 |
<p>Disclosed is a method for enhancing the expression of a protein in an RNA viral vector. Also disclosed is an RNA viral vector having enhanced expression performance. An AB5B protein is fused with a protein, and the resulting fusion protein is expressed with an RNA viral vector. In this manner, the expression level of the protein can be significantly increased. By utilizing the RNA viral vector as a gene delivery vector, it becomes possible to achieve an effective gene therapy, an effective gene vaccine, the effective production of a monoclonal antibody, and the like.</p> |
申请人 |
DNAVEC CORPORATION;INOUE, MAKOTO;SAEKI, KOICHI;YOU, JUN;TABATA, TOSHIAKI;IWASAKI, HITOSHI;SHU, TSUGUMINE;HASEGAWA, MAMORU |
发明人 |
INOUE, MAKOTO;SAEKI, KOICHI;YOU, JUN;TABATA, TOSHIAKI;IWASAKI, HITOSHI;SHU, TSUGUMINE;HASEGAWA, MAMORU |