发明名称 |
RNA SEQUENCE MOTIFS IN THE CONTEXT OF DEFINED INTERNUCLEOTIDE LINKAGES INDUCING SPECIFIC IMMUNE MODULATORY PROFILES |
摘要 |
Immunostimulatory polymers that contain certain sequence-dependent immunostimulatory RNA motifs and methods for the use of such immunostimulatory polymers and compositions containing such polymers are provided according to the invention. The sequence-dependent immunostimulatory RNA motifs and the polymers incorporating such motifs are potent and selective inducers of TLR7 and the TLR7-associated cytokine IFN-α.
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申请公布号 |
KR20100045508(A) |
申请公布日期 |
2010.05.03 |
申请号 |
KR20107005451 |
申请日期 |
2008.08.08 |
申请人 |
COLEY PHARMACEUTICAL GMBH |
发明人 |
JURK MARION;VOLLMER JORG HEINZ |
分类号 |
A61K48/00;A61K31/7105;A61K39/39;A61P11/06;C12N15/117 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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地址 |
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