摘要 |
<p>Provided is the use of a neutralizing, high affinity human anti-TNF alpha antibody, or antigen binding portion thereof, in the preparation of a medicament for treating psoriasis, wherein the medicament is adapted for biweekly administration and comprises a dosage of 10-150 mg of the neutralizing, high affinity human anti-TNF alpha antibody, or antigen binding portion thereof. Further provided are specific variants of the antibody and dosage regimens for such use.</p> |
申请人 |
ABBOTT BIOTECHNOLOGY LTD. |
发明人 |
BANERJEE, SUBHASHIS;TAYLOR, LORI K;SPIEGLER, CLIVE E;TRACEY, DANIEL EDWARD;CHARTASH, ELLIOT KEITH;HOFFMAN, REBECCA S;BARCHUK, WILLIAM T;YAN, PHILIP;MURTAZA, ANWAR;SALFELD, JOCHEN G;FISCHKOFF, STEVEN |