Disclosed are antibodies which bind to human OX40L, comprising a variable light chain and a variable heavy chain, characterized in that the variable heavy chain comprises CDR3 selected from SEQ ID NOs: 33-38 and/or the variable light chain comprises CDR3 selected from SEQ ID NOs: 51-57. Further disclosed is the use of the disclosed antibodies for the preparation of a medicament for the prophylaxis and treatment of inflammatory disorders. (62) Divided Out of 553333
申请公布号
NZ579022(A)
申请公布日期
2010.04.30
申请号
NZ20050579022
申请日期
2005.09.16
申请人
F. HOFFMANN-LA ROCHE AG
发明人
ENDL, JOSEF;EUGUI, ELSIE;FUENTES, MARIA ELENA;GRAUS, YVO;LABRIJN, ARAN FRANK;LANZENDOERFER, MARTIN;PARREN, PAUL;REBERS, FRANK;SCHUMACHER, RALF;SEEBER, STEFAN;VAN VUGT, MARTINE;VAN DE WINKEL, JAN