PROCESS FOR THE PREPARATION OF SUBSTANTIALLY OPTICALLY PURE REPAGLINIDE AND PRECURSORS THEREOF
摘要
<p>The invention relates to a process for preparing substantially optically pure repaglinide and pharmaceutically acceptable salts, solvates and esters thereof. The invention further relates to a process for preparing precursors of repaglinide and in particular for preparing ( S ) ( f ) - 1 - ( 2 -piperidino-phenyl ) -3 - methyl - I -butylamine.</p>
申请公布号
WO2010046360(A1)
申请公布日期
2010.04.29
申请号
WO2009EP63734
申请日期
2009.10.20
申请人
KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO;VEVERKA, MIROSLAV;VEVERKOVA, EVA;KLVANOVA, JANA;BOMBEK, SERGEJA;MERSLAVIC, MARJO;SMODIS, JANEZ
发明人
VEVERKA, MIROSLAV;VEVERKOVA, EVA;KLVANOVA, JANA;BOMBEK, SERGEJA;MERSLAVIC, MARJO;SMODIS, JANEZ