发明名称 |
Biomarkers of Mineralocorticoid Receptor activation |
摘要 |
The present invention relates to the use of Neutrophil Gelatinase-Associated Lipocalin (NGAL) and/or SERPINA3 as biomarkers of the Mineralocorticoid Receptor (MR) activation in a patient. More particularly, the present invention relates to a method for predicting the responsiveness of a patient to a treatment with a MR antagonist or an aldosterone synthase inhibitor, said method comprising determining in a biological sample obtained from said patient the expression level of the NGAL gene and/or of the SERPINA3 gene. |
申请公布号 |
AU2009306404(A1) |
申请公布日期 |
2010.04.29 |
申请号 |
AU20090306404 |
申请日期 |
2009.10.21 |
申请人 |
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) |
发明人 |
FREDERIC JAISSER;NICOLETTE FARMAN;YANNIS SAINTE-MARIE;CELINE LATOUCHE;MARJA STEENMAN |
分类号 |
C12Q1/68;G01N33/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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