发明名称 Uracil reductase inactivators
摘要 Uracil reductase inactivators, notably a 5-substituted uracil or 5,6-dihydro-5-substituted uracil, potentiate 5-flourouracil and find use particularly in the treatment of cancer. The 5-substituent is selected from bromo, ido, cyano, halo-substituted C1-4 alkyl, C2-6 alkenyl, 1-halo-C2-6 alkenyl and halo-substituted C2-6 alkynyl.
申请公布号 US7704971(B2) 申请公布日期 2010.04.27
申请号 US20060469515 申请日期 2006.09.01
申请人 SMITHKLINEBEECHAM CORPORATION 发明人 SPECTOR THOMAS;PORTER DAVID J. T.;RAHIM SAAD G.
分类号 A61K31/70;A61K31/7105;A61K;A61K31/505;A61K31/513;A61K45/00;A61K45/06;A61P35/00;C07D239/42;C07D239/54;C07H19/06 主分类号 A61K31/70
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