发明名称 Novel Heteroaryl Substituted Imidazo [1,2-A] Pyridine Derivatives
摘要 The present invention relates to novel heteroaryl substituted imidazopyridine derivatives, precursors thereof, and therapeutic uses of such compounds, having the structural formula (Ia) and to their pharmaceutically acceptable salt, compositions and methods of use. Furthermore, the invention relates to novel heteroaryl substituted imidazopyridine derivatives that are suitable for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. More specifically, the present invention relates to a method of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents.
申请公布号 US2010092385(A1) 申请公布日期 2010.04.15
申请号 US20080524019 申请日期 2008.01.21
申请人 ASTRAZENECA AB 发明人 VALLIN MICHAELA;MALMSTROM JONAS;PYRING DAVID;SLIVO CAN;WENSBO DAVID
分类号 A61K51/04;A61K31/437;A61K31/496;A61K31/5377;A61K49/00;A61K49/10;A61P25/28;C07D401/14;C07D413/14;C07D471/04 主分类号 A61K51/04
代理机构 代理人
主权项
地址