PHOTO-ACTIVATABLE THERAPEUTIC AGENTS AND METHODS OF USING

摘要

Novel photo-activatable pro-therapeutic agents and methods for their synthesis and use are described. The photo-activatable pro-therapeutic agents are inactive pro-forms of compounds that can be activated in situ, for example, by providing a pro-therapeutic agent to a subject and photo-activating the pro-therapeutic agent at a selected area of the subject. Also disclosed are methods for administering the photo-activatable pro-therapeutic agents to a subject then activating the pro-therapeutic agents at a selected area of the subject by exposing that area to light.