METHOD OF PRODUCING ALPHA-FORM GLUTAMIC ACID CRYSTALS

摘要

This present invention provides crystallization of α-form crystals preferentially which are metastable crystals without precipitating &bgr;-form crystals. This method allows for the precipitation of α-form crystals which are metastable crystals by combining (a) the process of achieving supersaturation by mixing an acidic solution with an aqueous solution containing glutamic acid to attain a pH at the isoelectric point of glutamic acid or lower, and (b) after a certain elapsed time, adding more of the aqueous glutamic acid solution to achieve a second supersaturation.